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. 2021 Jul 12;27(48):12380–12387. doi: 10.1002/chem.202101520

Scheme 1.

Scheme 1

Synthesis of R IPP and reaction with boron trifluoride diethyletherate to obtain R IPP_BF2 . i) 2‐Acetylpyridine:aldehyde:NH4OAc 1 : 2 : 5; AcOH, r.t., 7 days. ii) BF3⋅Et2O, Et3N, CH2Cl2, r.t.