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. 2021 Mar 19;64(6):687–697. doi: 10.1165/rcmb.2020-0453OC

Figure 1.

Figure 1.

 The gene expression profile of differentially expressed genes within the enriched regulation of blood coagulation gene ontology (GO) term for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–infected NHBEs. (A) Heatmap of selected genes in the regulation of blood coagulation GO term. Bolded genes represent differentially expressed genes as calculated by DESeq2 (P.adj < 0.05). (B) Pathway map of the extrinsic blood coagulation cascade (right) and the plasminogen activation system (left) with overlaid expression values. Blue asterisks indicate upregulation, black asterisks indicate no change, and red asterisks indicate downregulation. NHBE = normal human bronchial epithelial cell; P.adj = P adjusted.