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. 2021 Mar 19;64(6):687–697. doi: 10.1165/rcmb.2020-0453OC

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Copyright © 2021 by the American Thoracic Society

This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/). For commercial usage and reprints please contact Diane Gern (dgern@thoracic.org).

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Figure 4. — The gene expression profile of differentially enriched genes from RNA isolated from the BAL fluid (BALF) of patients with coronavirus disease (COVID-19). (A) Heatmap presentation of select differentially expressed genes presented in Figure 2 (NHBEs infected with SARS-CoV-2). The expression data presented in the heat map demonstrate the expression profile of those genes in BALF-derived samples. Bolded genes represent differentially expressed genes as calculated by DESeq2 (P.adj < 0.05). (B) Heatmap presentation of an expanded selection of all differentially enriched expressed genes within the enriched regulation of blood coagulation GO term (GO:0007596) from BALF-derived heathy control subjects and patient samples.