TABLE 1.
SOD1G93A | ||
---|---|---|
Male | Female | |
Brain (μg·g−1) | 7.93 ± 2.96, n = 5 | 8.36 ± 1.32, n = 5 |
Liver (μg·g−1) | 3.40 ± 1.25, n = 5 | 4.22 ± 1.39, n = 5 |
Plasma (μg·ml−1) | 1.22 ± 0.13, n = 5 | 0.83 ± 0.11, n = 5 |
WT | ||
---|---|---|
Male | Female | |
Brain (μg·g−1) | 4.07 ± 1.41, n = 5 | 5.76 ± 2.57, n = 5 |
Liver (μg·g−1) | 2.54 ± 0.98, n = 5 | 4.47 ± 1.12, n = 5 |
Plasma (μg·ml−1) | 0.69 ± 0.14, n = 5* | 1.37 ± 0.23, n = 5 |
Note: CTEP concentration in the brain (μg·g−1), liver (μg·g−1) and plasma (μg·ml−1) after 15‐day CTEP administration (4 mg·kg−1 every 24 h) starting at Day 90 in SOD1G93A and age‐matched WT mice. Data are mean ± SEM of five independent analyses.
P < 0.05, significantly different from female WT mice; two‐way ANOVA followed by Bonferroni's post hoc test.