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. 2021 Jul 26;60(35):19058–19062. doi: 10.1002/anie.202106517

Figure 4.

Figure 4

a) Secondary structure of mt‐tRNAThr with target C32 in orange. b) PAGE analysis of mt‐tRNAThr cleaved with AL112 and AK104. c) Secondary structure of mt‐tRNAGlu with target C49 in violet. d) PAGE analysis of mt‐tRNAGlu cleaved with AN05 and AK104. The cleavage reactions were performed at 37 °C. The arrows indicate the cleavage sites. Binding sites for DNAzymes are shown (binding arms in gray, catalytic core in green).