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. 2021 Jul 2;27(45):11554–11558. doi: 10.1002/chem.202101621

Scheme 4.

Scheme 4

Synthesis of 5‐(trifluoromethoxy)picolinonitrile 5ab. a) Current approach: multi‐step indirect synthesis. b) TEMPO‐catalyzed trifluoromethoxylation with BTMP. 19F NMR yields (internal standard=PhCF3), isolated yields in parentheses.