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. 2021 Jul 4;144(3):288–299. doi: 10.1111/acps.13335

TABLE 3.

Reliable improvement, reliable deterioration, remission, relative risks (RRs), and Numbers‐needed‐to‐be‐treated (NNT) of psychotherapies versus control groups

Psychotherapy Control groups Psychotherapy versus control
N Rate 95% CI I 2 95% CI N Rate 95% CI I 2 95% CI RR 95% CI I 2 95% CI NNT 95% CI
Reliable improvement at 2 (±1) months
RCI improvement (CAU) 81 0.59 0.54~0.64 87 85~89 76 0.30 0.26~0.34 82 78~85 1.85 1.62~2.10 83 79~86 3.9 3.0~5.4
RCI improvement (WL) 101 0.60 0.56~0.63 78 73~81 90 0.30 0.27~0.32 54 41~64 1.91 1.75~2.09 72 65~77 3.7 3.1~4.4
RCI improvement (PLA) 5 0.68 0.53~0.80 78 47~91 4 0.57 0.41~0.71 77 37~92 1.14 0.94~1.38 0 0~77 12.5 n.s.
Reliable deterioration at 2 months
RCI deterioration (CAU) 81 0.05 0.04~0.06 13 0~35 76 0.12 0.10~0.14 55 41~65 0.37 0.29~0.48 0 0~9 4.9 3.4~7.7
RCI deterioration (WL) 101 0.05 0.04~0.05 0 0~7 90 0.13 0.12~0.15 34 14~49 0.27 0.22~0.33 0 0~0 2.8 2.2~3.8
RCI deterioration (PLA) 5 0.02 0.01~0.06 0 0~0 5 0.07 0.04~0.11 0 0~0 0.34 0.13~0.88 0 0~36 7.4 2.1~104.8
Remission (HAM‐D <7) at 2 months
Remission (CAU) 22 0.26 0.20~0.33 74 60~83 21 0.12 0.09~0.18 57 30~74 2.19 1.40~3.42 37 0~62 7.0 3.4~20.8
Remission (WL) 27 0.34 0.27~0.41 67 50~78 22 0.09 0.06~0.12 0 0~23 4.39 3.29~5.86 0 0~0 3.3 2.3~4.9
Remission (PLA) 4 0.34 0.27~0.42 0 0~84 3 0.17 0.11~025 0 0~85 2.11 1.90~2.35 0 0~0 5.3 4.4~6.5