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. 2021 Aug 6;60(37):20301–20307. doi: 10.1002/anie.202108885

Figure 2.

Figure 2

Formation of dipyrrin cyclopeptides. Percent conversions were reported and determined by HPLC. a) The synthetic routes for dipyrrin‐GHK cyclopeptides, where the dipyrrin linker can be constructed by Methods A/B for the scope of meso bridge. b) The synthetic routes for constructing dipyrrin on different peptide chains containing two pyrrolyl groups, incorporating all proteinogenic amino acids of different ring sizes by Method Aa and/or Method Bb.