Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of inhibitors 7a, 7b, 7d, and 7e. Reagents and chemicals. (a) LiOH, THF-H2O, 23 °C, 30 min; (b) 5-chloro-3-pyridinol 6, EDC, DMAP, CH2Cl2, 23 °C, 12 h; (c) NaH, m-NO2-PhSO2Cl, THF, 23 °C, 24 h; (d) NaH, allylbromide, THF, 23 °C, 12 h; (e) 1N NaOH, EtOH-H2O, 85 °C, 3 h.
