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. Author manuscript; available in PMC: 2021 Sep 22.
Published in final edited form as: Ann Surg Oncol. 2017 Aug 24;24(12):3706–3714. doi: 10.1245/s10434-017-6060-7

Table 3.

Factors independently associated with microvascular invasion (MVI), RFS, and OS.

A. MVI
OR (95% CI) p-value
AFP* 5.471 (1.660-18.034) 0.005
Albumin* 0.780 (0.609-0.999) 0.049
Radiologic tumor size* 1.455 (1.133-1.869) 0.003
OR hazard ratio, CI confidence interval, AFP α-fetoprotein. *per 1 standard deviation increase.
B. RFS
HR (95% CI) p-value
Male 1.502 (1.090-2.068) 0.013
AFP* 1.303 (1.145-1.483) < 0.001
PLR* 1.292 (1.129-1.479) < 0.001
Microvascular invasion 1.539 (1.174-2.017) 0.002
Multiple nodules or satellites 1.826 (1.357-2.458) < 0.001
HR hazard ratio, CI confidence interval, AFP α-fetoprotein, PLR platelet to lymphocyte ratio. *per 1 standard deviation increase.
C. OS.
HR (95% CI) p-value
Age* 1.375 (1.171-1.614) < 0.001
Male 1.764 (1.241-2.508) 0.002
INR* 1.143(1.030-1.269) 0.012
PLR* 1.235 (1.057-1.444) 0.008
Microvascular invasion 1.763 (1.293-2.406) < 0.001
Multiple nodules or satellites 1.474 (1.067-2.037) 0.019
Tumor size* 1.297 (1.100-1.529) 0.002
Cirrhosis 2.458 (1.702-3.551) < 0.001
Steatosis 0.688 (0.497-0.952) 0.024
HR hazard ratio, CI confidence interval, INR international normalized ratio, PLR platelet to lymphocyte ratio. *per 1 standard deviation increase.