Table 3. Differences between patients with SARS-CoV-2 pneumonia clinical course of ≤4 weeks and >4 weeks (long COVID) from a 6 months follow-up in primary care (2020).
Patient´s characteristics | Follow-up Symptoms | Follow-up in primary care | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Sociodemographic | ≤4 weeks | >4 weeks | p-value | Symptoms | ≤4 weeks | >4 weeks | p-value | Primary Care | ≤4 weeks | >4 weeks | p-value |
n | 111 | 44 | Fever (>37,5°C)& | 6 (5.4) | 5 (11.1) | 0.210 | Days of follow-up$ | 50.0 (39.0, 73.0) | 81.0 (50.5, 103.0) | <0.001 | |
Sex (female)& | 52 (46.8) | 28 (63.6) | 0.050 | Cough& | 37 (33.3) | 28 (63.6) | <0.001 | Number of phone calls by GP or nurse during the follow-up# | 10.6 (5.0) | 16.0 (8.0) | <0.001 |
Age (mean) & | 60.1 (17.6) | 55.7 (14.2) | 0.140 | Dyspnoea& | 24 (21.6) | 25 (54.6) | <0.001 | Blood Test, day | 34.9 (25.5) | 36.1 (13.6) | |
Comorbidities | Myalgia& | 10 (9.1) | 12 (27.3) | 0.004 | Lymphocytes (10E3/ÂμL)$ | 2492.6 (956.8) | 2277.1 (789.7) | 0.240 | |||
Overweight (BMI >25)& | 61 (55.0) | 22 (50.0) | 0.370 | Asthenia& | 16 (14.4) | 25 (56.8) | <0.001 | D-dimer (μg/L)$ | 460.0 (260.0, 870.0) | 465.0 (280.0, 730.0) | 0.730 |
Hypertension& | 59 (53.2) | 12 (27.3) | 0.004 | Headache& | 7 (6.3) | 11 (25.0) | 0.001 | Ferritin (μg/L)$ | 164.0 (42.0, 330.0) | 143.0 (59.0, 410.0) | 0.900 |
Dyslipidaemia& | 45 (40.5) | 15 (34.1) | 0.460 | Chest pain& | 17 (15.3) | 8 (18.2) | 0.660 | CRP (mg/L)$ | 1.4 (0.3, 4.0) | 1.2 (0.4, 2.9) | 0.910 |
Type II Diabetes& | 18 (16.2) | 11 (25.0) | 0.210 | Dysgeusia& | 2 (1.8) | 1 (2.3) | 0.850 | Chest X-ray, day | 51.4 (27.4) | 56.7(33.3) | |
Asthma& | 17 (15.3) | 3 (6.8) | 0.150 | Anosmia& | 1 (0.9) | 3 (7.0) | 0.034 | Normal X-ray& | 71(64) | 25 (55.6) | 0.130 |
Smoke habit& | 10 (9.0) | 2(4.5) | 0.630 | GI symptoms& | 23 (20.7) | 18 (40.9) | 0.010 | COVID-19 Complications | |||
Chronic Kidney Disease& | 10 (9.0) | 1 (2.3) | 0.140 | Number of symptoms | ICU entry& | 1 (0.9) | 3 (6.8) | 0.036 | |||
Cancer& | 8 (7.2) | 2 (4.5) | 0.540 | None& | 27 (24.3) | 0 (0.0) | <0.001 | Home Oxygen Therapy& | 5 (4.5) | 3 (6.8) | 0.560 |
COPD& | 5 (4.5) | 1 (2.3) | 0.520 | ≤ 3& | 63 (56.8) | 24 (54.5) | <0.001 | Readmission& | 6 (5.4) | 3 (6.8) | 0.730 |
Heart failure& | 5 (4.5) | 1 (2.3) | 0.520 | ≥ 4& | 21 (18.9) | 20 (45.5) | <0.001 | Thromboembolism& | 2 (1.8) | 4 (9.1) | 0.034 |
&: number (%)
#: mean (standard deviation)
$: median (interquartile range), BMI (body mass index), COPD (chronic obstructive pulmonary disease), GI (gastrointestinal), ICU (intensive unit care), CRP (C reactive protein).