Table 3. Association between rs2660845 and exacerbation in individuals with early-onset asthma in PAGES and BREATHE non-montelukast users and in GoSHARE(b) individuals 12 months before being on montelukast.

Study	PAGES (n = 356)	BREATHE (n = 94)	GoSHARE(b) (n = 88)
OR (95% CI)	1.97 (0.927–4.187)	1.14 (0.246–5.36)	1.49 (0.532–4.18)
P-value	0.171	0.919	0.447

Odds of exacerbation rate on montelukast using an additive model adjusted for age, gender, age at 1st montelukast prescription or age at asthma onset and BMI when significant and available.

GoSHARE(b): individuals with age at first salbutamol, age at first inhaled corticosteroid and age at first montelukast prescription, all three under or at 18 years old.