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. 2021 Sep 8;11:710909. doi: 10.3389/fonc.2021.710909

Table 4.

Performance evaluation of three models in three cohorts.

Model Training cohort Internal validation cohort External validation cohort
AUC (95% CI) Sensitivity (%) Specificity (%) Accuracy (%) AUC (95% CI) Sensitivity (%) Specificity (%) Accuracy (%) AUC (95% CI) Sensitivity (%) Specificity (%) Accuracy (%)
Model1 0.820 (0.754–0.885) 61.80% 90.00% 74.22% 0.785 (0.663–0.906) 66.67% 86.67% 75.37% 0.808 (0.697–0.919) 66.67% 85.19% 75.00%
Model2 0.780 (0.707–0.853) 79.78% 68.57% 74.84% 0.794 (0.687–0.902) 66.67% 83.33% 73.91% 0.802 (0.690–0.915) 72.73% 81.48% 76.67%
Model3 0.874 (0.821–0.927) 64.05% 94.29% 77.36% 0.845 (0.744–0.946) 61.54% 100% 78.26% 0.841 (0.736–0.945) 87.88% 77.78% 83.34%

AUC, area under the curve; CI, confidence interval.