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SRGN affects the JAK/STAT signaling pathway in 143B cells. Western blot analysis of the expression of Bcl-2, JAK2, p-JAK2, STAT3, p-STAT3, and ACTIN. pcDNA3.1, means MOCK transfection with pcDNA3.1, and it was used as the empty control of the overexpression group; NC, negative control used as the control for siRNA experiments; * We set the quantized value of pcDNA3.1 and NC to 1.00. The other quantized values were compared with their respective experimental groups.
