Table 1. Baseline, laboratory and imaging characteristics.
| Variable | Total (n=432) | Severe group (n=125) | Non-severe group (n=307) | p value |
| Age(years) | 52.88±16.91 | 59.60±16.65 | 50.14±16.26 | <0.0001 |
| Gender | 0.072 | |||
| Female-n (%) | 202(47) | 50(40) | 152(49.5) | |
| Male-n (%) | 230(53) | 75(60) | 155(50.5) | |
| Clinical symptom-n (%) | ||||
| Fever | 308(71.3) | 94(75.2) | 214(69.7) | 0.252 |
| Fatigue | 128(29.6) | 46(36.8) | 82(26.7) | 0.037 |
| Dyspnea | 35(8.1) | 20(16) | 15(4.9) | < 0.0001 |
| Pharyngalgia | 34(7.9) | 12(9.6) | 22(7.2) | 0.394 |
| Cough | 270(62.5) | 84(67.2) | 186(60.6) | 0.198 |
| Chest tightness | 47(10.9) | 22(17.6) | 25(8.1) | 0.004 |
| Diarrhea | 20(4.6) | 6(4.8) | 14(4.6) | 0.914 |
| Myalgia | 46(10.6) | 19(15.2) | 27(8.8) | 0.05 |
| Expectoration | 130(30.1) | 35(28) | 95(30.9) | 0.545 |
| Headache | 19(4.4) | 6(4.8) | 13(4.2) | 0.795 |
| Poor appetite | 53(12.3) | 19(15.2) | 34(11.1) | 0.236 |
| Comorbidities-n (%) | ||||
| Hypertension | 92(21.3) | 53(42.4) | 39(12.7) | <0.0001 |
| Diabetes | 56(13) | 31(24.8) | 25(8.1) | <0.0001 |
| COPD | 25(5.8) | 13(10.4) | 12(3.9) | 0.009 |
| Renal insufficiency | 9(2.1) | 8(6.4) | 1(0.3) | <0.0001 |
| Cardiac insufficiency | 8(1.9) | 7(5.6) | 1(0.3) | 0.01 |
| Hepatic insufficiency | 30(6.9) | 16(12.8) | 14(4.6) | 0.002 |
| Anemia | 13(3.0) | 7(5.6) | 6(2.0) | 0.089 |
| Clinical laboratory | ||||
| White blood cell-10^9/L | 5.25±2.52 | 5.76±3.19 | 5.04±2.16 | 0.023 |
| Lymphocyte-10^9/L | 1.28±0.62 | 1.04±0.70 | 1.37±0.55 | <0.0001 |
| Neutrophil-10^9/L (IQR) | 2.98(2.11-4.18) | 3.41(2.32-5.50) | 2.82(2.08-3.77) | <0.0001 |
| CRP-mg/L(IQR) | 22.32(9.15-37.7) | 45.2(14.85-55.8) | 22.32(7.7-22.32) | <0.0001 |
| Platelet-10^9/L | 173.02±80.88 | 163.03±83.74 | 177.08±79.47 | 0.102 |
| D-dimer-μg/ml (IQR) | 0.55(0.44-0.82) | 0.62(0.50-1.42) | 0.52(0.42-0.68) | <0.0001 |
| LDH-U/L(IQR) | 210(170-267.75) | 265(207.5-356) | 196(162-235) | <0.0001 |
| NLR (IQR) | 2.33(1.51-3.94) | 3.84(2.06-7.13) | 2.03(1.41-3.25) | <0.0001 |
| CT manifestations | ||||
| CT score (IQR) | 6(4-7.75) | 6(4-9) | 6(4-7) | <0.0001 |
| Bilateral lung involved-n (%) | 359(83.1) | 120(96) | 239(77.9) | <0.0001 |
| Ground glass opacity-n (%) | 426(98.6) | 124(99.2) | 302(98.4) | 0.830 |
| Consolidation-n (%) | 96(22.2) | 40(32) | 56(18.2) | 0.002 |
| Pleural effusion-n (%) | 5(1.2) | 4(3.2) | 1(0.3) | 0.042 |
| Pleural thickening-n (%) | 5(1.2) | 1(0.8) | 4(1.3) | 1.000 |
Abbreviation: COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; NLR, neutrophil - to- lymphocyte ratio; LDH, lactate dehydrogenase.