Table 3.

Lesions size changes of the two groups during the study

Group	Before	After 6 th week	After 12 th mouth	P -value time	P -value group	P-value Time+ group
Oral + liposomal	1.74 ± 0.58	0.34 ± 0.69	0.079 ± 34	<0.001	0.37	0.16
Oral group	1.65 ± 0.46	0.55 ± 0.58	0.27 ± 0.38	<0.001

Values are mean ± SD, P-values resulted from linear mixed effect model.