Table 3.

Working hours needed for monthly therapy

Working hours needed to cover the low and-high cost therapy
ACE-inhibitors								Sartans
INN		2016		2017		2018	2019	INN		2016	2017	2018	2019
Enalapril	Lowest price medicinal product	0.417		0.376		0.347	0.309	Losartan	Lowest price medicinal product	0.591	0.533	0.511	0.455
Enalapril	highest price medicinal product	1.440		1.298		1.244	1.109	Losartan	highest price medicinal product	2.988	1.901	1.280	0.987
Lisinopril	Lowest price medicinal product	0.699		0.605		0.580	0.495	Eprosartan*		4.957	4.467	4.283	3.820
Lisinopril	highest price medicinal product	2.887		2.602		2.407	2.147	Valsartan	Lowest price medicinal product	0.654	0.589	0.566	0.505
Perindopril	Lowest price medicinal product	0.790		0.616		0.589	0.375	Valsartan	highest price medicinal product	2.030	1.829	1.554	1.386
Perindopril	highest price medicinal product	2.242		1.777		1.638	1.461	Irbesartan	Lowest price medicinal product	1.228	0.824	0.737	0.658
Ramipril	Lowest price medicinal product	0.172		0.155		0.148	0.132	Irbesartan	highest price medicinal product	5.148	4.639	4.448	1.533
Ramipril	highest price medicinal product	1.061		0.956		0.916	0.786	Candesartan	Lowest price medicinal product	0.449	0.384	0.359	0.320
Quinapril	Lowest price medicinal product	0.987		0.890		0.853	0.761	Candesartan	highest price medicinal product	2.972	3.451	2.104	1.623
Quinapril	highest price medicinal product	1.988		1.791		1.188	1.060	Telmisartan	Lowest price medicinal product	0.941	0.770	0.710	0.634
Fosinopril	Lowest price medicinal product	0.991		0.893		1.258	1.121	Telmisartan	highest price medicinal product	2.334	2.103	1.836	1.638
Fosinopril	highest price medicinal product	2.169		1.954		1.874	1.652	olmesartan	Lowest price medicinal product	3.904	1.091	1.128	1.006
Trandolapril	Lowest price medicinal product	0.950		0.856		1.127	0.778	olmesartan	highest price medicinal product	8.070	8.955	6.709	4.024
Trandolapril	highest price medicinal product	3.172		2.859		2.741	2.444	Ca-antagonists
Zofenopril	Lowest price medicinal product	3.568		2.923		2.744	2.487	amlodipine	Lowest price medicinal product	0.141	0.127	0.121	0.121
Zofenopril	highest price medicinal product	6.470		5.830		5.591	4.986	amlodipine	highest price medicinal product	5.925	5.340	5.120	0.922
B- blockers								felodipine	Lowest price medicinal product	0.393	0.354	0.339	0.339
Metoprolol	Lowest price medicinal product	1.169	1.091		1.015		1.015	felodipine	highest price medicinal product	2.591	2.335	1.977	2.972
Metoprolol	highest price medicinal product	5.447	6.977		6.691		6.691	nifedipine	Lowest price medicinal product	0.643	0.570	0.548	0.548
Atenolol	Lowest price medicinal product	0.637	0.574		0.550		0.550	nifedipine	highest price medicinal product	1.077	0.970	0.930	0.970
Atenolol	highest price medicinal product	0.913	0.823		0.577		0.577	nimodipine*		16.685	15.036	14.419	14.419
bisoprolol	Lowest price medicinal product	0.450	0.406		0.370		0.370	lacidipine*		1.508	1.360	1.304	1.304
Bisoprolol	highest price medicinal product	4.668	4.206		4.034		6.180	lercanidipine	Lowest price medicinal product	1.026	0.661	0.847	0.847
Nebivolol	Lowest price medicinal product	1.181	0.864		0.828		0.828	lercanidipine	highest price medicinal product	2.217	1.501	1.695	2.017
Nebivolol	highest price medicinal product	3.560	3.208		3.077		3.077	-
Carvedilol	Lowest price medicinal product	1.106	0.997		0.956		0.956	-
Carvedilol	highest price medicinal product	11.929	10.750		10.309		5.749	-

^*One trademark is available on the market.