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. 2021 Sep 22;22(3):357–366. doi: 10.1016/S1473-3099(21)00566-1

Table 3.

Estimated SARS-CoV-2 outcomes averted through vaccination programme by number of doses received, Jan 3 to April 10, 2021

Population size SARS-CoV-2 infections averted COVID-19-related hospitalisations averted Severe or critical COVID-19-related hospitalisations averted COVID-19-related deaths averted
Individuals who were at least partly vaccinated*
Age 16–24 years 1 258 389 17 443 (14 839 to 20 047) 347 (−6 to 699) 57 (−34 to 149) 5 (−5 to 15)
Age 25–34 years 1 231 583 20 762 (17 393 to 24 131) 904 (222 to 1586) 229 (−35 to 493) 10 (−11 to 32)
Age 35–44 years 1 156 876 24 255 (19 821 to 28 690) 1273 (339 to 2207) 579 (8 to 1150) 26 (−28 to 81)
Age 45–54 years 981 651 28 634 (22 440 to 34 828) 2544 (785 to 4303) 1595 (283 to 2907) 130 (−117 to 377)
Age 55–64 years 782 447 24 421 (18 141 to 30 701) 3316 (1169 to 5463) 2361 (601 to 4120) 326 (−198 to 850)
Age 65–74 years 675 369 20 332 (13 242 to 27 422) 4908 (1551 to 8265) 3575 (835 to 6315) 1045 (−282 to 2373)
Age 75–84 years 319 285 15 025 (7456 to 22 594) 6868 (1828 to 11 908) 5461 (1085 to 9838) 2070 (−262 to 4402)
Age ≥85 years 133 311 7793 (2567 to 13 018) 4437 (733 to 8141) 3575 (322 to 6828) 1920 (−242 to 4083)
Age ≥16 years 6 538 911 158 665 (144 640 to 172 690) 24 597 (18 942 to 30 252) 17 432 (12 770 to 22 094) 5532 (3085 to 7982)
Age ≥65 years 1 127 965 43 150 (31 582 to 54 717) 16 213 (9053 to 23 372) 12 611 (6423 to 18 800) 5035 (1393 to 8678)
Individuals who were fully vaccinated
Age 16–24 years 1 258 389 10 282 (8755 to 11 810) 220 (−8 to 448) 33 (−19 to 86) 4 (−3 to 11)
Age 25–34 years 1 231 583 12 919 (10 842 to 14 997) 580 (128 to 1032) 140 (−24 to 305) 6 (−4 to 16)
Age 35–44 years 1 156 876 17 063 (13 983 to 20 144) 877 (211 to 1543) 398 (−0·4 to 797) 18 (−16 to 52)
Age 45–54 years 981 651 21 698 (17 112 to 26 283) 1931 (568 to 3293) 1199 (193 to 2205) 101 (−79 to 281)
Age 55–64 years 782 447 19 219 (14 384 to 24 053) 2598 (899 to 4297) 1844 (455 to 3234) 253 (−143 to 649)
Age 65–74 years 675 369 16 337 (10 694 to 21 981) 3954 (1221 to 6687) 2865 (653 to 5078) 831 (−213 to 1874)
Age 75–84 years 319 285 12 390 (6121 to 18 659) 5762 (1504 to 10 020) 4599 (906 to 8291) 1669 (−227 to 3565)
Age ≥85 years 133 311 6092 (1886 to 10 297) 3545 (544 to 6546) 2847 (223 to 5472) 1469 (−217 to 3154)
Age ≥16 years 6 538 911 116 000 (106 072 to 125 928) 19 467 (15 200 to 23 735) 13 925 (10 408 to 17 445) 4351 (2559 to 6140)
Age ≥65 years 1 127 965 34 819 (25 428 to 44 211) 13 261 (7300 to 19 222) 10 311 (5169 to 15 454) 3969 (1022 to 6914)
Individuals who were partly vaccinated
Age 16–24 years 1 258 389 7161 (6084 to 8237) 127 (2 to 251) 24 (−15 to 63) 1 (−2 to 4)
Age 25–34 years 1 231 583 7843 (6551 to 9134) 324 (94 to 554) 89 (−11 to 188) 4 (−7 to 16)
Age 35–44 years 1 156 876 7192 (5838 to 8546) 396 (128 to 664) 181 (8 to 353) 8 (−12 to 29)
Age 45–54 years 981 651 6936 (5328 to 8545) 613 (217 to 1010) 396 (90 to 702) 29 (−38 to 96)
Age 55–64 years 782 447 5202 (3757 to 6648) 718 (270 to 1166) 517 (146 to 886) 73 (−55 to 201)
Age 65–74 years 675 369 3995 (2548 to 5441) 954 (330 to 1578) 710 (182 to 1237) 214 (−69 to 499)
Age 75–84 years 319 285 2635 (1335 to 3935) 1106 (324 to 1888) 862 (179 to 1547) 401 (−35 to 837)
Age ≥85 years 133 311 1701 (681 to 2721) 892 (189 to 1595) 728 (99 to 1356) 451 (−25 to 929)
Age ≥16 years 6 538 911 42 665 (38 568 to 46 762) 5130 (3742 to 6517) 3507 (2362 to 4649) 1181 (526 to 1842)
Age ≥65 years 1 127 965 8331 (6154 to 10 506) 2952 (1753 to 4150) 2300 (1254 to 3346) 1066 (371 to 1764)

Data are n or number of cases averted with 95% CI in parentheses.

*

Individuals who were at least partly vaccinated were those who received at least one dose of BNT162b2 with at least 14 days of follow-up after the first dose.

Fully vaccinated individuals are people who received two doses of BNT162b2 with at least 7 days of follow-up after the second dose.

Partly vaccinated individuals are people who received only one dose of BNT162b2 with at least 14 days of follow-up after the first dose or two doses with less than 7 days of follow-up after the second dose.