Figure 3. Ross River virus (RRV) transmission capability of Brisbane mosquitoes remained consistent when considering physiological traits alone (A) or also considering ecological traits (B, C).

(A) Physiological response of mosquitoes to experimental infection with RRV, summarized using the area under (AUC) of their estimated infection probability versus dose curves multiplied by the area under their transmission probability versus time curves. Points show median estimates; the error bars in each panel are 95% confidence intervals (CIs) that combine the uncertainty from all statistical sub-models used to obtain the estimates presented in that panel (see Figure 1 and Box 1 for these components). AUC is used only to quantify mosquito physiological competence; raw infection and transmission profiles (pictured in Appendix 1—figure 3 and Appendix 1—figure 4, respectively) are used in calculations of half-cycle and complete-cycle transmission. The ordering of vector species based on highest (top) to lowest (bottom) physiological competence in A is conserved in B and C to aid visualization of vector order changes among panels. (B) Vector-to-host transmission; matrices show the median numbers of hosts infected by each vector species, while the points show infection totals (sums across matrix rows), with error bars. (C) Vector-host-vector transmission. As in B, the matrices show median numbers of next-generation vector infections for all vector species pairs, while the points show sums across rows of the matrices (left plot) and the proportion of infections in the second generation that are in the same species as the original infected individual (center plot).