Resource Table

Unique stem cell lines identifier	1. SCVIi003-A 2. SCVIi004-A 3. SCVIi005-A
Alternative names of stem cell lines	1. SCVIi003-A: SCVI-385, SCVI385 2. SCVIi004-A: SCVI-410, SCVI410 3. SCVIi005-A: SCVI-740, SCVI740
Institution	Stanford Cardiovascular Institute, SCVI
Contact information of distributor	Dr. Joseph C. Wu (joewu@stanford.edu)
Type of cell lines	iPSCs
Origin	Human
Cell Source	Blood
Clonality	Clonal
Method of reprogramming	Integration-free Sendai virus expressing human OCT4, SOX2, KLF4, and c-MYC
Multiline rationale	Non-isogenic cell lines obtained from three patients with heterozygous mutation in PKP2
Gene modification	Yes
Type of modification	Spontaneous mutation
Associated disease	Arrhythmogenie right ventricular dysplasia/cardiomyopathy (OMIM: 107970)
Gene/locus	PKP2 (12p11.21) SCVIi003-A: Heterozygous; PKP2; c.2065_2070delinsG SCVIi004-A: Heterozygous; PKP2; c.235C>T SCVIi005-A: Heterozygous; PKP2; c.1725_1728dup
Method of modification	N/A
Name of transgene or resistance	N/A
Inducible/constitutive system	N/A
Date archived/stock date	1. SCVIi003-A (04-27-2017) 2. SCVIi004-A (05-17-2017) 3. SCVIi005-A (05-30-2017)
Cell line repository/bank	https://hpscreg.eu/cell-line/SCVIi003-A https://hpscreg.eu/cell-line/SCVIi004-A https://hpscreg.eu/cell-line/SCVIi005-A
Ethical approval	The generation of the lines was approved by the Administrative Panel on Human Subjects Research (IRB) under IRB #29904 “Derivation of Human Induced Pluripotent Stem Cells (Biorepository)”.