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Ketamine suppresses viability and proliferation of liver cells in vitro and in vivo. (A and B) HepG2 and Huh7 cells were treated with ketamine (Keta) for indicated time, cell viability was detected by CCK-8 assay. Colony formation (C and D) and EdU assay (E) were performed to detect cell proliferation. (F and G) Xenograft mice model was established by using HepG2 cells. Tumor growth curve (F) and tumor weight (G) were recorded. **p < 0.01.
