Table 2.

Study characteristic, demographics and LoE of studies meeting inclusion criteria

Study	Year	Type of Study	Type of Prosthesis (Fixed bearing/mobile bearing)	No. of Patients	No. of Knees	mean Age, range (years)	BMI categories	Follow-up period (months)	Secondary outcomes of Interest	Level of Evidence (LoE)
Seyler [36]	2009	Cohort	Fixed bearing	68	80	72(44–91)	< 30, > 30	60 months (24–128)	–	2b
Bonutti [8]	2011	Retrospective	Fixed bearing	67	80	66.5(45–81)	< 35, > 35	36 months (24 to 84)	–	3b
Plate [33]	2015	Retrospective	Fixed bearing	672	746	64	< 18.5, 18.5–25, 25–30, 30–35, 35–40, 40–45, > 45	33.6 months (24 +)	–	3b
Zengerink [45]	2015	Retrospective	Fixed bearing	130	141	60.5	< 30, > 30	60 months (24–144)	Unexplained pain	3b
Venkatesh [40]	2016	Cohort	Fixed bearing	148	175	61.7	< 30, > 30	67.2 months (24–120)	Unexplained Pain, aseptic loosening, KSS	2b
Woo [42]	2017	Retrospective	Fixed bearing	673	673	62	< 25, 25–30, 30–35, > 35	64 months (30–102)	Unexplained pain, aseptic loosening	3b
Murray [30]	2013	Cohort	Mobile bearing	–	2438	64	< 25, 25–30, 30–35, > 35, 35–40, 40–45, > 45	55.2 months (24–144)	Unexplained pain, infection, aseptic loosening, OKS, KSS	2b
Xu [44]	2019	Cohort	Fixed bearing	184	184	59.5	> 30, < 30	Minimum 120 months	Aseptic loosening, infection, KSS, OKS	2b
Polat [34]	2019	Retrospective	Mobile bearing	104	104	60.2	> 30, < 30	46 months (31.4– 60.6)	Aseptic loosening, infection	3b