Table 1.
Demographic and clinical characteristics of infants in the final cohort (N=36) and of all recruited infants (N=43).
| Baseline Characteristic | N=36 | N=43 |
|---|---|---|
|
| ||
| Maternal age (years) | 28.1 (5.0) | 27.2 (5.2) |
| Gestational age at birth (weeks) | 25.5 (1.6) | 25.6 (1.7) |
| Birth weight (grams) | 753.2 (146) | 762.3 (143) |
| Male | 58.3% | 58.1% |
| Small for gestational age (<10th percentile) | 11.1% | 14.0% |
| Apgar score <5 at 5 minutes | 22.2% | 23.3% |
| Late-onset sepsis (+/− blood culture) | 63.9% | 65.1% |
| Major surgery (with general anesthesia) | 5.6% | 9.3% |
| Duration of positive pressure support (days) | 47 (23,75) | 47 (22, 75) |
| White matter injury on structural MRI* | 16.7% | 18.6% |
| Postmenstrual age at MRI (weeks) | 38.5 (2.2) | 38.5 (2.2) |
Note: Non-percentage values are expressed as mean (SD), except for duration of positive pressure support, which is expressed as median (25th, 75th percentile)
*
Defined as lesions in the white matter, including diffuse punctate lesions, cystic periventricular leukomalacia, encephalomalacia, and/or moderate/severe atrophy.