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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Circ Heart Fail. 2021 Aug 25;14(9):e008076. doi: 10.1161/CIRCHEARTFAILURE.120.008076

Table 2.

Determinants of Physical Frailty in Heart Failure*

OR [95%CI] p value
Women 4.63 [1.81, 11.84] 0.001
Body mass index (kg/m2) 1.06 [0.99, 1.13] 0.07
History of asthma, emphysema, chronic bronchitis, or chronic obstructive pulmonary disease 2.71 [0.98, 7.50] 0.06
Type 2 diabetes 3.34 [1.26, 8.86] 0.016
Prescribed an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker 0.21 [0.07, 0.61] 0.004
Model Pseudo R2 / Area Under the ROC Curve 25.2% / 0.83
*

Reference group is non-physically frail

Results reported were factors retained in backward stepwise regression model (p < 0.10 retention) that included: age; sex; married/partnered; body mass index; Charlson Comorbidity Index total score; history of asthma, emphysema, chronic bronchitis, or COPD; Stage 3 chronic kidney disease; type 2 diabetes; time with heart failure; New York Heart Association functional class; type of heart failure (heart failure with reduced vs. preserved ejection fraction); left ventricular ejection fraction; serum hemoglobin; prescribed a beta blocker; and prescribed an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker.

Abbreviations: ROC, Receiver Operating Characteristic