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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Biomed Pharmacother. 2021 Aug 13;142:112024. doi: 10.1016/j.biopha.2021.112024

Fig. 3.

Fig. 3.

The anti-cancer and anti-inflammatory effects of silymarin. Silymarin can inhibit NF-B by preventing the degradation of inhibitor kappa B (IB), and thus decreases oxidative stress and inflammatory responses. Silymarin inhibits STAT3 and ERK1/2 signaling pathways that can lead to suppression of oncogenesis, cell proliferation, cell migration, and iNOS gene expression.

Figure adapted from [147].