Figure 3: AT1aR deletion attenuated medial remodeling in male Fbn1C1041G/+ mice.
A, Representative images of Verhoeff’s elastin staining in ascending aortic sections from male WT, AT1aR-/-, Fbn1C1041G/+, and AT1aR-/- x Fbn1C1041G/+ mice. Green bar=100 μm. B, Number of breaks per high powered field detected in aortic sections. C, Medial thickness as measured by the distance between the inner elastic lamina and external elastic lamina in aortic sections. * p<0.05, *** p<0.001. (n=5/group).