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. 2021 Sep 22;11:18899. doi: 10.1038/s41598-021-98336-7

Table 3.

Associations between uterine pulsatility index (PI) and metabolic and psychological parameters in menopausal patients (N = 65).

Uterine PI (in menopausal women)
Univariate analysis Multivariate analysis*
Pearson’s r P β P
Clinical and metabolic parameters
BMI (kg/m2) 0.526  < 0.0001 0.511  < 0.0001
Waist circumference (cm) 0.491  < 0.0001 0.474 0.001
SBP (mm Hg) 0.091 0.485 0.083 0.578
DBP (mm Hg) − 0.107 0.413 − 0.016 0.918
Fasting glycemia (g/L) 0.197 0.165 0.189 0.211
Total Cholesterol (mg/dL) 0.120 0.390 0.055 0.721
HDL Cholesterol (mg/dL) − 0.250 0.074 − 0.260 0.088
Triglycerides (mg/dL) 0.181 0.203 0.202 0.192
LDL Cholesterol (mg/dL) 0.181 0.213 0.098 0.538
Fasting insulin (mUI/L) 0.416 0.018 0.481 0.006
HOMA-IR index 0.425 0.019 0.494 0.009
HbA1c (mmol/mol) 0.448 0.003 0.564  < 0.0001
Psychological parameters
MHQ Total score − 0.031 0.841 0.089 0.618
BUT-A global severity index (GSI) 0.436 0.003 0.652  < 0.0001
BUT-A weight phobia (WP) 0.314 0.038 0.543 0.001
BUT-A body image concern (BIC) 0.531  < 0.0001 0.669  < 0.0001
BUT-A avoidance (AV) 0.361 0.016 0.569 0.001
BUT-A compulsive self-monitoring (CSM) 0.070 0.653 0.185 0.270
BUT-A depersonalization (DEP) 0.430 0.004 0.684  < 0.0001
BUT-B positive symptom distress index (PSDI) 0.414 0.006 0.518 0.001
BUT-B positive symptom Total (PST) 0.095 0.548 0.271 0.131

*Data adjusted for age, smoking habit, and years since menopause. After 10% False Discovery Rate calculation, the cut-off for significant p-value was adjusted at < 0.038. Bold indicates statistical significance (p value < 0.038).

BMI body mass index, BUT Body Uneasiness Test, HbA1c glycated hemoglobin, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment—insulin resistance, LDL low-density lipoprotein, MHQ Middlesex Hospital Questionnaire, PI pulsatility index.