Table 3.
Associations between uterine pulsatility index (PI) and metabolic and psychological parameters in menopausal patients (N = 65).
| Uterine PI (in menopausal women) | ||||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis* | |||
| Pearson’s r | P | β | P | |
| Clinical and metabolic parameters | ||||
| BMI (kg/m2) | 0.526 | < 0.0001 | 0.511 | < 0.0001 |
| Waist circumference (cm) | 0.491 | < 0.0001 | 0.474 | 0.001 |
| SBP (mm Hg) | 0.091 | 0.485 | 0.083 | 0.578 |
| DBP (mm Hg) | − 0.107 | 0.413 | − 0.016 | 0.918 |
| Fasting glycemia (g/L) | 0.197 | 0.165 | 0.189 | 0.211 |
| Total Cholesterol (mg/dL) | 0.120 | 0.390 | 0.055 | 0.721 |
| HDL Cholesterol (mg/dL) | − 0.250 | 0.074 | − 0.260 | 0.088 |
| Triglycerides (mg/dL) | 0.181 | 0.203 | 0.202 | 0.192 |
| LDL Cholesterol (mg/dL) | 0.181 | 0.213 | 0.098 | 0.538 |
| Fasting insulin (mUI/L) | 0.416 | 0.018 | 0.481 | 0.006 |
| HOMA-IR index | 0.425 | 0.019 | 0.494 | 0.009 |
| HbA1c (mmol/mol) | 0.448 | 0.003 | 0.564 | < 0.0001 |
| Psychological parameters | ||||
| MHQ Total score | − 0.031 | 0.841 | 0.089 | 0.618 |
| BUT-A global severity index (GSI) | 0.436 | 0.003 | 0.652 | < 0.0001 |
| BUT-A weight phobia (WP) | 0.314 | 0.038 | 0.543 | 0.001 |
| BUT-A body image concern (BIC) | 0.531 | < 0.0001 | 0.669 | < 0.0001 |
| BUT-A avoidance (AV) | 0.361 | 0.016 | 0.569 | 0.001 |
| BUT-A compulsive self-monitoring (CSM) | 0.070 | 0.653 | 0.185 | 0.270 |
| BUT-A depersonalization (DEP) | 0.430 | 0.004 | 0.684 | < 0.0001 |
| BUT-B positive symptom distress index (PSDI) | 0.414 | 0.006 | 0.518 | 0.001 |
| BUT-B positive symptom Total (PST) | 0.095 | 0.548 | 0.271 | 0.131 |
*Data adjusted for age, smoking habit, and years since menopause. After 10% False Discovery Rate calculation, the cut-off for significant p-value was adjusted at < 0.038. Bold indicates statistical significance (p value < 0.038).
BMI body mass index, BUT Body Uneasiness Test, HbA1c glycated hemoglobin, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment—insulin resistance, LDL low-density lipoprotein, MHQ Middlesex Hospital Questionnaire, PI pulsatility index.