TABLE 3.
Sensitivity of a DmRAD54−/−/DmKu70−/− double mutant to X rays and MMS
| Agent and dose | Genotype | Total no. of fliesa | Ratiob | Sensitivityc |
|---|---|---|---|---|
| None | Wild type | 767 | 9 | |
| DmKu70−/− | 341 | 4 | ||
| DmRAD54−/− | 294 | 3.4 | ||
| DmRAD54−/−/DmKu70−/− | 105 | 1.2 | ||
| X rays (6 Gy) | Wild type | 546 | 9 | |
| DmKu70−/− | 76 | 1.2 | 3 | |
| DmRAD54−/− | 31 | 0.5 | 7 | |
| DmRAD54−/−/DmKu70−/− | 2 | 0.03 | 40 | |
| MMS (0.06 mM) | Wild type | 373 | 9 | |
| DmKu70−/− | 73 | 1.8 | 2 | |
| DmRAD54−/− | 16 | 0.4 | 8 | |
| DmRAD54−/−/DmKu70−/− | 10 | 0.2 | 6 |
a
Number of flies recovered.
b
Ratio of the number of flies of each genotype relative to the others, with the value for wild-type (heterozygous and homozygous) flies set at 9 for comparison with the Mendelian ratio of 9:3:3:1 (wild type to DmKu70−/− to DmRAD54−/− to DmRAD54−/−/DmKu70−/− flies).
c
Obtained by dividing the ratio of the untreated sample by the ratio of the treated sample.