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. 2021 Sep 9;12:659250. doi: 10.3389/fneur.2021.659250

Table 2.

Technical details and main findings of the eight studies included in this meta-analysis.

References Field Acquisition voxel (mm3) No. of directions Coordinate system No. of coordinates Type of analysis Main findings of FA
Sigurdsson et al. (27) 3 T 1 × 1 × 2 32 MNI 0 TBSS Negative
Wen et al. (11) 3 T 1 × 1 × 1 30 MNI 12 TBSS Decreased FA in the body of corpus callosum, forceps major, right inferior longitudinal fasciculus, right inferior fronto-occipital fasciculus, right corticospinal tract, left frontal lobe subgyral, left anterior thalamic radiations, and bilateral superior longitudinal fasciculus
Müller-Vahl et al. (25) 1.5 T NA 12 MNI 11 VBA Decreased FA in the bilaterally in the medial frontal gyrus, the pars opercularis of the left inferior frontal gyrus, the middle occipital gyrus, the right cingulate gyrus, and the medial premotor cortex
Jeppesen et al. (28) 3 T 1 × 1 × 1 15 MNI 0 TBSS Negative
Liu et al. (29) 1.5 T NA 15 MNI 0 TBSS Negative
Govindan et al. (17) 3.0 T 3 × 3 × 3 6 MNI 0 TBSS Negative
Neuner et al. (24) 1.5 T 2 × 2 × 2 30 MNI 9 TBSS Decreased FA in the corticospinal tract, the corpus callosum and long association fiber pathways such as the inferior fronto-occipital fascicle and the superior longitudinal fascicle as well as in the uncinate fascicle
Thomalla et al. (26) 3 T 2 × 2 × 2 24 MNI 1 VBA Increased FA in the mesial part of the left central and postcentral gyrus

No., number; FA, fractional anisotropy; MNI, Montreal Neurological Institute; TBSS, tract-based spatial statistics; VBA, voxel-based analysis.