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. 2021 Sep 9;12:722237. doi: 10.3389/fneur.2021.722237

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Copyright © 2021 Clarke, Arnett, Bukhari, Khalilidehkordi, Jimenez Sanchez, O'Gorman, Sun, Prain, Woodhall, Silvestrini, Bundell, Abernethy, Bhuta, Blum, Boggild, Boundy, Brew, Brownlee, Butzkueven, Carroll, Chen, Coulthard, Dale, Das, Fabis-Pedrini, Gillis, Hawke, Heard, Henderson, Heshmat, Hodgkinson, Kilpatrick, King, Kneebone, Kornberg, Lechner-Scott, Lin, Lynch, Macdonell, Mason, McCombe, Pereira, Pollard, Ramanathan, Reddel, Shaw, Spies, Stankovich, Sutton, Vucic, Walsh, Wong, Yiu, Barnett, Kermode, Marriott, Parratt, Slee, Taylor, Willoughby, Brilot, Vincent, Waters and Broadley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lesions and features on MRI of brain and spinal cord associated with multiple sclerosis: periventricular hyperintense T2 white matter lesions (arrows) on axial FLAIR image of the brain (A); subcortical T2 white matter lesions (arrows) on axial FLAIR image of the brain (B); juxtacortical hyperintense T2 white matter lesion (arrow) on axial proton density image of the brain (C); cortical hyperintense T2 lesion (arrow) on sagittal FLAIR image of the brain (D); cerebellar hyperintense T2 lesions (arrows) on sagittal FLAIR image of the brain (E); ovoid hyperintense T2 periventricular lesion (arrow) on axial FLAIR image of the brain (F); large supratentorial T2 lesion (arrow) on sagittal FLAIR image of the brain (G); Dawson's finger lesions (arrows) on sagittal FLAIR image of the brain (H); right cerebellar peduncle hyperintense T2 lesion (arrow) on axial T2 image of the brain (I); pyramidal corpus callosum hyperintense T2 lesion (arrow) on sagittal FLAIR image of the brain (J); splenium hyperintense T2 lesion (arrow) on axial (K) and sagittal (L) FLAIR images of the brain; Gd-enhancing T1 lesions of periventricular (arrow) (M), juxtacortical (arrows) (N), splenium (arrow) (O) regions on axial T1 images of the brain and ring-enhancing lesion (arrow) on coronal T1 image of the brain (P); hypointense T1 (black hole) lesions (arrows) on axial T1 image of the brain (Q); short segment C3 T2 lesion (arrow) on sagittal T2 image of the cervical spinal cord (R); and hyperintense T2 partial cord lesion (arrow) on axial T2 image of the cervical spinal cord (S).