Table 1.
Patient Demographics (n = 106).
| Characteristic | No. (%) | HS-mGPS, No. | |||
|---|---|---|---|---|---|
| 0 | 1 | 2 | P valuea | ||
| Age | |||||
| <66 years | 58 (54.7) | 36 | 14 | 8 | .037 |
| ≥66 years | 48 (45.3) | 21 | 23 | 4 | |
| Sex | |||||
| Male | 94 (88.7) | 49 | 34 | 11 | .636 |
| Female | 12 (11.3) | 8 | 3 | 1 | |
| ECOG PS | |||||
| 0 | 83 (78.3) | 45 | 25 | 5 | .007 |
| 1 | 20 (18.9) | 12 | 9 | 4 | |
| 2 | 3 (2.8) | 0 | 3 | 3 | |
| HPV | |||||
| Positive | 44 (41.5) | 31 | 9 | 4 | .013 |
| Negative | 62 (58.5) | 26 | 28 | 8 | |
| Smoking status | |||||
| Nonsmoker | 22 (20.8) | 12 | 9 | 1 | |
| Smoker (current or ex) | 84 (79.2) | 45 | 28 | 11 | |
| Drinking history | |||||
| Yes | 29 | 16 | 10 | 3 | .964 |
| None | 76 | 40 | 27 | 9 | |
| Tumor stage | |||||
| T1 | 11 (10.4) | 5 | 5 | 1 | .332 |
| T2 | 45 (42.5) | 29 | 11 | 5 | |
| T3 | 21 (19.9) | 12 | 8 | 1 | |
| T4 | 29 (27.2) | 11 | 13 | 5 | |
| Nodal stage | |||||
| N0 | 22 (20.8) | 12 | 9 | 1 | .227 |
| N1 | 34 (32.1) | 23 | 7 | 4 | |
| N2 | 43 (40.6) | 20 | 18 | 5 | |
| N3 | 7 (6.5) | 2 | 3 | 2 | |
| AJCC stage | |||||
| I | 29 (27.3) | 20 | 6 | 3 | .123 |
| II | 16 (15.1) | 10 | 4 | 2 | |
| III | 14 (13.2) | 9 | 5 | 0 | |
| IV | 47 (44.4) | 18 | 22 | 7 | |
| Tumor location | |||||
| Palatine tonsils | 72 (68.0) | 43 | 21 | 8 | .163 |
| Base of the tongue | 26 (24.4) | 10 | 14 | 2 | |
| Posterior pharyngeal wall | 4 (3.8) | 1 | 2 | 1 | |
| Soft palate | 4 (3.8) | 3 | 0 | 1 | |
| Treatment | |||||
| Radiotherapy | 17 (16.1) | 11 | 5 | 1 | .743 |
| Chemoradiotherapy | 84 (79.2) | 43 | 30 | 11 | |
| TOVS + ND | 5 (4.7) | 3 | 2 | 0 | |
Abbreviations: AJCC, American Joint Committee on Cancer; ECOG PS, Eastern Cooperative Oncology Group performance status; HPV, human papillomavirus; HS-mGPS, high-sensitivity modified Glasgow prognostic score; ND, neck dissection; TOVS, transoral videolaryngoscopic surgery.
a
Appropriate statistical test (Student t test, Mann-Whitney U, χ2 test, or Fisher exact test) conducted between HS-mGPS.