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. 2021 Sep 9;9:730240. doi: 10.3389/fcell.2021.730240

FIGURE 5.

FIGURE 5

Correlation and survival analysis of immune infiltrating cells with ICB and lenvatinib target genes. (A) The correlation between ICB and lenvatinib target genes and tumor infiltration immune cells. The cancer types indicated with a green box if ≥8 positive correlations and more than 4 of them have an r ≤ –0.15, and the cancer types indicated with an orange or red box if ≥8 negative correlations and more than 4 of them have an r ≥ 0.15. (B) The relationship between immune infiltrates and survival outcomes in malignancy. The blue square represents high immune infiltration decreases risk and predicts longer survival time in certain tumors (P < 0.05, Z < 0), and the red square represents high immune infiltration increases risk and predicts shorter survival time in certain tumors (P < 0.05, Z > 0). Z represents normalized coefficient. DC, dendritic cells; M2, M2 macrophages; MDSC, myeloid-derived suppressor cells.