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. 2021 Sep 9;12:712178. doi: 10.3389/fpsyt.2021.712178

Table 3.

Model coefficients for neuroticism mediation.

Antecedent Consequent
M (Neuroticism) Y (Sleep disturbances)
Coeff. SE p Coeff. SE p
X (CNR1 rs6454674 genotype) a 2.619 1.052 0.013 c' 0.077 0.050 0.125
M (Neuroticism) b 0.011 0.003 <0.001
Constant iM 43.557 0.780 <0.001 iY 0.331 0.118 0.005
R2 = 0.018 R2 = 0.061
F(1,340) = 6.193, p = 0.013 F(2,339) = 10.986, p < 0.001

X, Predictor; M, Mediator; Y, Outcome; Coeff., Coefficient; SE, Standard Error; a = path from X to M, c' = path from X to Y controlling for M, b = path from M to Y controlling for X.