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. 2021 Sep 9;8:694238. doi: 10.3389/fcvm.2021.694238

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Copyright © 2021 Liang, Cao, He, Li, Huang, Ma, Li, Huang, Huang and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AKR1C3 was a ferroptosis-related biomarker for acute myocardial infarction (AMI) diagnosis. (A) AKR1C3 was significantly downregulated in AMI samples of the GSE48060 cohort. (B) The receiver operating characteristic (ROC) curve for the diagnostic value of AKR1C3 in GSE48060. (C) AKR1C3 was downregulated in H9C2 cells treated with 5 nM erastin. (D) AKR1C3 was significantly downregulated in AMI samples of the local cohort. (E) The ROC curve for the diagnostic value of AKR1C3 in the local cohort. *p < 0.05.