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. 2021 Sep 9;8:694238. doi: 10.3389/fcvm.2021.694238

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Copyright © 2021 Liang, Cao, He, Li, Huang, Ma, Li, Huang, Huang and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical relevance. (A) AKR1C3 was downregulated in acute myocardial infarction (AMI) patients with smoking history. (B) The cases with smoking history had a higher logical score, which meant that these people were more likely to be diagnosed as AMI. (C) HOXB4 and the logical score were significantly correlated with the value of NTproBNP. (D) AKR1C3 and the logical scores had a significant association with CK and CK-MB. NTproBNP, N-terminal-pro-B-type natriuretic peptide; CK, creatine kinase; CK-MB, creatine kinase MB fraction; *p < 0.05. ns, not significant.