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. 2021 Sep 9;12:718404. doi: 10.3389/fphys.2021.718404

FIGURE 4.

FIGURE 4

Key regulators of t-tubule structure during development, adulthood, and heart failure of various etiologies. HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; Dnm2, dynamin-2; Mtm1, myotubularin-1; JPH2, junctophilin-2; Cav3, caveolin-3.