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. 2021 Sep 23;43(1):59–66. doi: 10.1007/s10072-021-05612-5

Table 2.

Qualitative and quantitative variables across expression of depressive symptoms

Expression of depressive symptoms p value
Yes No
Age 35.10 (29–40) 36.26 (32–41) 0.310
Gender 0.247
  Male 22 (15.2%) 28 (20.4%)
  Female 123 (84.8%) 109 (79.6%)
Education 0.004
  Middle school degree 8 (5.5%) 2 (1.5%)
  High school diploma 43 (29.7%) 21 (15.3%)
  Associate/bachelor degree 69 (47.6%) 80 (58.4%)
  Graduate degree 25 (17.2%) 34 (24.8%)
Occupational status 0.015
  Employed 46 (31.7%) 62 (45.9%)
  Unemployed 99 (68.3%) 73 (54.1%)
Marital status 0.022
  Single 44 (30.3%) 49 (35.8%)
  Married 76 (52.4%) 79 (57.7%)
  Divorced 25 (17.2%) 9 (6.6%)
MS type 0.547
  CIS 9 (6.2%) 10 (7.3%)
  RRMS 97 (66.9%) 98 (71.5%)
  PPMS 11 (7.6%) 11 (8.0%)
  SPMS 28 (19.3%) 18 (13.1%)
Disease duration 7.31 (3.5–10) 7.41 (3–10) 0.930
Treatment duration 6.04 (3–7.5) 6.4 (3–9) 0.513
Hospital admission due to MS attacks 2.64 (1–3) 1.79 (0–2) 0.048
EDSS 2.97 (1.5–4.5) 2.78 (1.5–4) 0.335
Drug type 0.080
  Immunomodulatory 75 (51.7%) 85 (62.0%)
  Immunosuppressive 70 (48.3%) 52 (38.0%)
Past psychiatric history 0.064
  Yes 35 (24.1%) 21 (15.3%)
  No 110 (75.9%) 116 (84.7%)
COVID-19 infection 0.573
  Yes 12 (8.3%) 14 (10.2%)
  No 133 (91.7%) 123 (89.8%)
Fear of COVID-19 18.93 (14–24) 15.88 (11.5–19)  ≤ 0.0001

CIS, clinically isolated syndrome; RRMS, relapsing–remitting multiple sclerosis; PPMS, primary progressive multiple sclerosis; SPMS, secondary progressive multiple sclerosis; EDSS, expanded disability status scale; BDI, Beck depression inventory; BAI, Beck anxiety inventory.