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. 2021 Sep 9;12:735125. doi: 10.3389/fimmu.2021.735125

Table 2.

Correlations between CD38hiHLA-DR+ percentage and soluble immune checkpoints, cytokines, chemokines, and growth factors in patients infected with SARS-CoV2.

Characteristics R value P values
Cytokines, chemokines, and growth factors
 HGF 0.576 <0.0001
 IL-18 0.530 <0.0001
 IL-1RA 0.519 0.00013
 MCP-1 0.504 0.00022
 RANTES 0.435 0.00179
 IL-10 0.403 0.00409
 SCF 0.401 0.00429
 IL-8 0.392 0.00529
 IL-21 0.390 0.00558
 IL-1alpha 0.359 0.01128
 IFN-gamma 0.342 0.01603
 IL-4 0.317 0.02646
 SDF-1alpha 0.306 0.03247
 IL-22 0.303 0.03431
 IL-6 0.299 0.03721
 GRO-alpha 0.288 0.04774
 BDNF −0.306 0.03266
Soluble immune checkpoints
 TIM-3 0.549 <0.0001
 CD27 0.459 0.00090
 LAG-3 0.411 0.00339
 IDO 0.401 0.00425
 BTLA 0.386 0.00621
 CD152 0.361 0.01087
 CD137 0.349 0.01411
 PD-1 0.346 0.01473
 CD80 0.329 0.02095
 CD28 0.285 0.04694