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. 2021 Sep 9;11:682710. doi: 10.3389/fonc.2021.682710

Figure 1.

Figure 1

SLC25A21 is downregulated in BCa and negatively associated with poor prognosis in BCa patients. (A) Expression levels of SLC25A21 mRNA in BCa and pair-matched noncancerous tissue samples. (B–D) Analysis of SLC25A21 expression in BCa compared with noncancerous tissue according to RNA-seq in TCGA database and BCa microarray profile (GSE3167 and GSE68020) (E) Expression analysis of SLC25A21 protein in BCa and normal bladder mucosa tissues by IHC. Scale bars, 100 μm (200x) or 50 μm (400x). (F) Correlation between SLC25A21 protein expression and overall survival in BCa patients (log-rank P =0.044).