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. 2021 Sep 9;11:682710. doi: 10.3389/fonc.2021.682710

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Copyright © 2021 Wang, Gao, Hu, Zeng, Yang, Chen and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SLC25A21 overexpression suppresses BCa cell proliferation in vivo. (A) SLC25A21 overexpression inhibited subcutaneous tumor formation in nude mice. EJ cells with SLC25A21 upregulation and control cells were inoculated into nude mice (n = 5 per group). (A) The xenografts of 30 days after ectopic-subcutaneous implantation of with SLC25A21 overexpressing and control cells into nude mice. (B, C) The effect of SLC25A21 overexpression on BCa tumor growth was evaluated based on tumor volume (B) and tumor weight (C) in the two groups. *P < 0.05.