TABLE 3.
The top 20 most significant enriched KEGG pathway terms and the target genes of hsa-miR-146a-5p.
| Term | ID | p | Gene IDs | Genes |
| Chagas disease (American trypanosomiasis) | hsa05142 | 0.00104666 | 3,654; 6,352 | IRAK1; CCL5 |
| Toll-like receptor signaling pathway | hsa04620 | 0.00108614 | 3,654; 6,352 | IRAK1; CCL5 |
| Pyrimidine metabolism | hsa00240 | 0.04690483 | 7,372 | UMPS |
| Thyroid cancer | hsa05216 | 0.01349153 | 8,030 | CCDC6 |
| Apoptosis—multiple species | hsa04215 | 0.01527736 | 5,366 | PMAIP1 |
| Prion diseases | hsa05020 | 0.01616913 | 6,352 | CCL5 |
| Notch signaling pathway | hsa04330 | 0.02194705 | 8,650 | NUMB |
| Drug metabolism—other enzymes | hsa00983 | 0.02106023 | 7,372 | UMPS |
| Type II diabetes mellitus | hsa04930 | 0.02194705 | 5,581 | PRKCE |
| Staphylococcus aureus infection | hsa05150 | 0.02592837 | 3,075 | CFH |
| NOD-like receptor signaling pathway | hsa04621 | 0.02592837 | 6,352 | CCL5 |
| Cytosolic DNA-sensing pathway | hsa04623 | 0.02901436 | 6,352 | CCL5 |
| Epithelial cell signaling in Helicobacter pylori infection | hsa05120 | 0.03077363 | 6,352 | CCL5 |
| p53 signaling pathway | hsa04115 | 0.03121298 | 5,366 | PMAIP1 |
| Leishmaniasis | hsa05140 | 0.0334069 | 3,654 | IRAK1 |
| Pertussis | hsa05133 | 0.03384512 | 3,654 | IRAK1 |
| Platinum drug resistance | hsa01524 | 0.03384512 | 5,366 | PMAIP1 |
| Complement and coagulation cascades | hsa04610 | 0.03559613 | 3,075 | CFH |
| Aldosterone synthesis and secretion | hsa04925 | 0.03647051 | 5,581 | PRKCE |
| ErbB signaling pathway | hsa04012 | 0.03952494 | 2,066 | ERBB4 |