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. 2021 Sep 9;8:716840. doi: 10.3389/fmed.2021.716840

Table 5.

Subgroup analysis of the association between hyperuricemia and adverse outcomes.

Factors Subgroup HR (95% CI) Interaction P-value
Age <65 years 2.396 (0.865–6.582) 0.677
≥65 years 1.769 (0.673–4.648)
Sex Male 2.963 (1.055–8.327) 0.412
Female 1.624 (0.571–4.609)
Hypertension Yes 1.026 (0.379–2.773) 0.048
No 4.314 (1.564–11.906)
Diabetes Yes 1.646 (0.275–9.863) 0.784
No 2.155 (1.008–4.603)
Smoking Yes 3.238 (0.913–11.481) 0.408
No 1.741 (0.731–4.152)
Atrial fibrillation Yes 0.431 (0.045–4.145) 0.137
No 2.538 (1.208–5.335)
Hyperlipidaemia Yes 0.503 (0.052–4.839) 0.175
No 2.596 (1.230–5.435)
LVEF <50 2.147 (0.744–6.191) 0.636
≥50 1.519 (0.570–4.049)
eGFR <60 2.784 (0.591–13.119) 0.488
≥60 1.466 (0.574–3.747)

BMI, body mass index; LVEF, left ventricular ejection fraction; eGFR, estimated Glomerular filtration rate; HR, hazard ratio; CI, confidence interval.