Table 5.
Comparison between MA and control group.
| SNP | Model |
Allele/ Genotype |
MA N = 26 % |
Control N = 120 % |
P value |
Crude Analysis COR(95% Cl) |
Adjusted Analysis AOR(95% Cl) |
P value |
|---|---|---|---|---|---|---|---|---|
|
rs2651899 (PRDM16) |
Allele | A | 33(63.46) | 188(78.33) | 0.0234* | 2.082(1.095–3.958) | ||
| G | 19(36.54) | 52(21.67) | ||||||
|
Genotype |
AA | 10(38.46) | 78(65) | |||||
| AG vs. AA | 13(50) | 32(26.67) | 0.014* | 3.3169(1.261–7.962) | 4.165(1.552–11.175) | 0.005** | ||
| GG vs. AA | 3(11.54) | 10(8.33) | 0.250 | 2.340(0.550–9.960) | 2.389(0.552–10.346) | 0.244 | ||
| Dominant | AA | 10(38.46) | 78(65) | |||||
| AG + GG | 16(61.54) | 42(35) | 0.015* | 2.971(1.239–7.7125) | 3.620(1.445–9.066) | 0.006** | ||
|
rs11172113 (LRP1) |
Allele | T | 35(67.31) | 166(69.16) | 0.7930 | 1.090(0.5739–2.069) | ||
| C | 17(32.69) | 74(30.83) | ||||||
|
Genotype |
TT vs. TT | 12(46.15) | 53(44.16) | |||||
| CT | 11(42.31) | 60(50) | 0.645 | 0.810(0.330–1.987) | 1.012(0.386–2.652) | 0.981 | ||
| CC vs. TT | 3(11.54) | 07(5.84) | 0.401 | 1.893(0.426–8.404) | 1.857(0.416–8.276) | 0.417 | ||
| Dominant | TT | 12(46.15) | 53(44.16) | |||||
| CT + CC | 14(53.85) | 67(55.84) | 0.853 | 0.923(0.394–2.162) | 1.144(0.464–2.819) | 0.770 | ||
|
rs10166942 (TRPM8) |
Allele | T | 44(84.62) | 198(82.5) | 0.713 | 0.8571(0.376–1.954) | ||
| C | 8(15.38) | 42(17.5) | ||||||
|
Genotype |
TT | 21(80.77) | 84(70) | |||||
| CT vs. TT | 2(7.69) | 30(25) | 0.086 | 0.267(0.059–1.206) | 0.306(0.066–1.429) | 0.312 | ||
| CC vs. TT | 3(11.54) | 06(5) | 0.354 | 2.000(0.462–8.664) | 1.873(0.426–8.233) | 0.406 | ||
| Dominant | TT | 21(80.77) | 84(70) | |||||
| CT + CC | 5(19.23) | 36(30) | 0.273 | 0.556(0.194–1.588) | 0.631(0.216–1.842) | 0.399 |
Data presented as number (N) and percentage (%)
COR; Crude odds ratio, AOR; Adjusted odds ratio Cl; Confidence Interval
*p < 0.05, **p < 0.01, ***p < 0.001 statistically significant
Adjusted for age and sex