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. 2021 Sep 18;15:3953–3963. doi: 10.2147/DDDT.S325790

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© 2021 Li et al.

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Safety of combined therapy with CpG and the mRNA vaccine. (A–L) Selected clinical biochemistry parameters (serum AST, ALT, ALP, total protein, cholesterol, bilirubin, albumin, etc.) in NC, CpG, mRNA and combination-treated mice (n≥4). (M) The liver was examined histologically, and representative images of mice injected with CpG and the mRNA vaccine are presented. *p<0.5, **p<0.01.