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. 2021 May 4;13(5):e1718. doi: 10.1002/wnan.1718

FIGURE 4.

FIGURE 4

Lipid‐mRNA vaccine mediated significantly efficacy in HPV‐positive tumors. E7‐lipid‐mRNA vaccine promoted the infiltration of memory CD8+ T lymphocytes (a), complete remission of HPV16‐positive tumors (b), secretion of proinflammatory factors (c), and inhibition of anti‐PD‐L1 refractory tumors (d). (Reprinted with permission from Grunwitz et al. (2019). Copyright © 2020 Informa UK Limited