Figure S1.
Identification of involved tissues, related to Effector genes and biological pathways and STAR Methods
Heatmap depicting tissue-specific gene-regulatory region enrichment significance (-log10 P value) for all osteoarthritis GWAS phenotypes. Tissue/cell type (full name, E-identifier, group name) and P value (-log10) of all significant enrichments (p < 1.3x10−8) are shown. Enrichment was calculated using all osteoarthritis associated lead SNVs and the fine-mapped variants, per osteoarthritis phenotype and all together. Only rows and columns containing a significant enrichment (p < 1.3x10−8) for all osteoarthritis phenotypes (Total) are shown. OA: osteoarthritis.