Selectivity profile of pyrazoline-based TZD inhibitors against a panel of human HDACs. IC₅₀ values are means, and errors were obtained from statistical analysis of non-linear regression fits to sets of 10 data points.

IC50 (μM)
Compound	HDAC1	HDAC2	HDAC3	HDAC4	HDAC6	HDAC7	HDAC8
13j	4.9	13	9.1	0.7 ± 0.3	39	>50	10 ± 1.0
14c	>50	>50	>50	0.88 ± 4	7.6	>50	>50
14j	11	21	11	0.8 ± 0.2	13	6.7	25 ± 7.0