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. 2021 Jul 27;12(9):1540–1554. doi: 10.1039/d1md00125f

IC50 of HUVECs by compounds 13b, 13d, 13j, 14a, 14c–14e, 14j, and 15g.

graphic file with name d1md00125f-u1.jpg
Sr. no. Code IC50a (μM) A ring B ring
1 13b 2 Phenyl 2-Cl phenyl
2 13d >10 Phenyl 4-CF3 phenyl
3 13j >10 Phenyl 3,4-DiCl phenyl
4 14a >10 4-F phenyl Phenyl
5 14c 0.7 4-F phenyl 2-Furyl
6 14d 6 4-F phenyl 4-CF3 phenyl
7 14e >10 4-F phenyl 4-F phenyl
8 14j 2 4-F phenyl 3,4-DiCl phenyl
9 15g >10 2,4-DiF phenyl 4-Tolyl
10 STS 0.5
a

Assays were performed in replicate (n ≥ 2).