Mondazzi 1993.

Methods	Generation of the allocation sequence: unclear (not reported). Allocation concealment: unclear (not reported). Blinding: inadequate (no blinding). Follow‐up: Inadequate. Six months after treatment. The number or reasons for dropouts and withdrawals were not described.
Participants	Patients with anti‐HCV positive chronic hepatitis.
Interventions	Prednisone plus interferon group: all patients received lymphoblastoid interferon alpha‐n1 three million units three times/week for one year plus prednisone 20 mg/day for eight weeks, 15 mg/day for two weeks, and 10 mg/day until the end of 12th month. Interferon group: was administrated as above.
Outcomes	ALT, liver histology, and flu‐syndrome.
Notes	Only abstract. No information on health economics was provided.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear