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| Methods | Randomized controlled trial Double blinded Multicenter Parallel group | |
| Participants | Inpatients with active osteoarthritis of the knee Country :Germany N = 200 Mean age: 54 years Female: 48% Male: 52% | |
| Interventions | GS 500 mg PO TID versus Ibuprofen 400 PO TID Duration: 4 weeks | |
| Outcomes | Lequesne Index Global investigator derived Safety | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Low risk | A ‐ Adequate |
